Article
Impact of colonoscopic screening in male and female Lynch syndrome carriers with an MSH2 mutation.
Clinical genetics - 1 Nov 2012
Stuckless S, Green J S, Morgenstern M, Kennedy C, Green R C, Woods M O, Fitzgerald W, Cox J, Parfrey P S
Abstract excerpt
The lifetime risk of developing colorectal cancer (CRC) in Lynch syndrome (LS) carriers is very high. To determine the impact of colonoscopic screening in 54 male and 98 female MSH2 mutation carriers, outcomes were compared with 94 males and 76 females who were not screened. CRC incidence and survival in the screened group were compared to that expected, derived from the non-screened group. To correct for...
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