Article
Development of colorectal tumors in colonoscopic surveillance in Lynch syndrome.
Gastroenterology - 1 Oct 2007
Mecklin Jukka-Pekka, Aarnio Markku, Läärä Esa, Kairaluoma Matti V, Pylvänäinen Kirsi, Peltomäki Päivi, Aaltonen Lauri A, Järvinen Heikki J
Abstract excerpt
BACKGROUND & AIMS: Mutation carriers in Lynch syndrome families have a high risk for developing colorectal cancer during their lifetime. This study was designed to assess the cumulative risk for the development of colorectal adenoma or carcinoma in prospective colonoscopic surveillance. METHODS: Data from the Finnish Hereditary Colorectal Cancer Registry electronic database on 420 Lynch syndrome mutation carriers...
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