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Article

EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy

10 Nov 2010

Abstract excerpt

The M-band is the prominent cytoskeletal structure that cross-links the myosin and titin filaments in the middle of the sarcomere. To investigate M-band alterations in heart disease, we analyzed the expression of its main components, proteins of the myomesin family, in mouse and human cardiomyopathy. Cardiac function was assessed by echocardiography and compared to the expression pattern of myomesins evaluated...

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PMID: 21069531
DOI: 10.1007/s00395-010-0131-2

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