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Article

Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death.

Human molecular genetics - 15 Feb 2009

Zheng Ming, Cheng Hongqiang, Li Xiaodong, Zhang Jianlin, Cui Li, Ouyang Kunfu, Han Liang, Zhao Ting, Gu Yusu, Dalton Nancy D, Bang Marie-Louise, Peterson Kirk L, Chen Ju

Abstract excerpt

Accumulating data suggest a link between alterations/deficiencies in cytoskeletal proteins and the progression of cardiomyopathy and heart failure, although the molecular basis for this link remains unclear. Cypher/ZASP is a cytoskeletal protein localized in the sarcomeric Z-line. Mutations in it...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19028670
DOI: 10.1093/hmg/ddn400
PMCID: PMC2722217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19028670-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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