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Article

Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction.

The Journal of biological chemistry - 14 Jan 2011

Resseguie Mary E, da Costa Kerry-Ann, Galanko Joseph A, Patel Mukund, Davis Ian J, Zeisel Steven H

Abstract excerpt

When dietary choline is restricted, most men and postmenopausal women develop multiorgan dysfunction marked by hepatic steatosis (choline deficiency syndrome (CDS)). However, a significant subset of premenopausal women is protected from CDS. Because hepatic PEMT (phosphatidylethanolamine N-methyl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21059658
DOI: 10.1074/jbc.M110.106922
PMCID: PMC3020773

Genes

PEMT
FOXA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21059658-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction.PMID 21059658Read ↗

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