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Phosphatidylethanolamine <i>N</i> ‐methyltransferase <i>(PEMT)</i> gene expression is induced by estrogen in human and mouse primary hepatocytes

24 Apr 2007

Abstract excerpt

Choline is an essential nutrient for humans, though some of the requirement can be met by endogenous synthesis catalyzed by phosphatidylethanolamine N-methyltransferase (PEMT). Premenopausal women are relatively resistant to choline deficiency compared with postmenopausal women and men. Studies in animals suggest that estrogen treatment can increase PEMT activity. In this study we investigated whether the PEMT...

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PMID: 17456783
DOI: 10.1096/fj.07-8227com

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