Article
Selection of CD4+CD8+ thymocytes by complex formation with medulla-derived epithelial cells.
Cellular immunology - 1 Mar 1990
Hugo P, Potworowski E F
Abstract excerpt
The role of lymphostromal complexes in T-cell differentiation is far from elucidated, mainly because a clear association of a particular stromal cell type with a distinct thymocyte subset has never been identified. Using an in vitro system, detecting the adherence of thymocytes to a thymic medullary epithelial cell line (E-5), we showed that the phenotype of these thymocytes was that of cortical type: Thy-1hi,...
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