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Article

Oral-aboral patterning and gastrulation of sea urchin embryos depend on sulfated glycosaminoglycans.

Mechanisms of development - 1 Jan 2000

Bergeron Karl-Frederik, Xu Xing, Brandhorst Bruce P

Abstract excerpt

Glycosaminoglycans (GAGs) are a heavily sulfated component of the extracellular matrix (ECM) implicated in a variety of cell signaling events involved in patterning of embryos. Embryos of the sea urchin Strongylocentrotus purpuratus were exposed to several inhibitors that disrupt GAG function during development. Treatment with chlorate, a general inhibitor of sulfation that leads to undersulfated GAGs, reduced...

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Identifiers

PMID: 21056656
DOI: 10.1016/j.mod.2010.11.001

Genes

ALK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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