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Article

Evaluation of developmental phenotypes produced by morpholino antisense targeting of a sea urchin Runx gene.

BMC biology - 7 May 2004

Coffman James A, Dickey-Sims Carrie, Haug Jeffrey S, McCarthy John J, Robertson Anthony J

Abstract excerpt

BACKGROUND: Runx transcription factors are important regulators of metazoan development. The sea urchin Runx gene SpRunt was previously identified as a trans-activator of the CyIIIa actin gene, a differentiation marker of larval aboral ectoderm. Here we extend the functional analysis of SpRunt, using morpholino antisense oligonucleotides (morpholinos) to interfere with SpRunt expression in the embryo. RESULTS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15132741
DOI: 10.1186/1741-7007-2-6
PMCID: PMC419381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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