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Article

ABCC5 is required for cAMP-mediated hindgut invagination in sea urchin embryos.

Development (Cambridge, England) - 15 Oct 2015

Shipp Lauren E, Hill Rose Z, Moy Gary W, Gökırmak Tufan, Hamdoun Amro

Abstract excerpt

ATP-binding cassette (ABC) transporters are evolutionarily conserved proteins that pump diverse substrates across membranes. Many are known to efflux signaling molecules and are extensively expressed during development. However, the role of transporters in moving extracellular signals that regulate embryogenesis is largely unexplored. Here, we show that a mesodermal ABCC (MRP) transporter is necessary for...

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Identifiers

PMID: 26395488
DOI: 10.1242/dev.126144
PMCID: PMC4631766

Genes

ABCC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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