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Article

Variable influence of mutational patterns in reverse-transcriptase domain on replication capacity of hepatitis B virus isolates from antiviral-experienced patients.

Clinica chimica acta; international journal of clinical chemistry - 30 Jan 2011

Ji Dong, Liu Yan, Si Lan-Lan, Li Le, Chen Guo-Feng, Xin Shao-Jie, Zhao Jin-Min, Xu Dongping

Abstract excerpt

BACKGROUND: Various mutations in reverse-transcriptase domain (RT) of hepatitis B virus (HBV) polymerase may develop during antiviral therapy. The influence of these mutational patterns on HBV replication capacity remains to be fully clarified. METHODS: Nine clones containing complete HBV genomes...

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Source

Identifiers

PMID: 21056552
DOI: 10.1016/j.cca.2010.10.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21056552-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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