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Article

Mutations in reverse transcriptase region of HBV affect Hepatitis B surface antigen titers and its correlation with HBV DNA.

Journal of infection in developing countries - 30 Nov 2019

Shen Hongyu, Chen Chunhua, Ye Chunyan, Zhang Hongyu, Hang Shuangxiong, Chen Min, Zhu Zhen, Xue Yuan, Liu Longgen

Abstract excerpt

INTRODUCTION: The impact of mutations in the reverse transcriptase region of HBV on serum HBsAg titer and its correlation with HBV DNA is largely unknown. METHODOLOGY: A total of 644 patients, with a history of lamivudine or adefovir dipivoxil resistance who underwent genotypic resistance tests, were enrolled in this study. Serum HBsAg, hepatitis B e antigen and HBV DNA were quantified, and the HBV RT region was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32087080
DOI: 10.3855/jidc.11447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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