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Article

In vivo priming of HIV-specific CTLs determines selective cross-reactive immune responses against poorly immunogenic HIV-natural variants.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2002

Boissonnas Alexandre, Bonduelle Olivia, Antzack Ariane, Lone Yu-Chun, Gache Cécile, Debre Patrice, Autran Brigitte, Combadière Behazine

Abstract excerpt

Degeneracy of the TCR repertoire might allow for cross-recognition of epitope variants. However, it is unclear how the first encounter with HIV Ags determines recognition of emerging epitope variants. This question remains crucial in the choice of HIV vaccine sequences given the virus variability...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12244162
DOI: 10.4049/jimmunol.169.7.3694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12244162-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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