Article
Lack of association between ACE and bradykinin B2 receptor gene polymorphisms and ACE inhibitor-induced coughing in hypertensive Koreans.
Journal of clinical pharmacy and therapeutics - 1 Oct 2009
Woo S W, Bang S, Chung M W, Jin S K, Kim Y S, Lee S H
Abstract excerpt
BACKGROUND & OBJECTIVE: Angiotensin converting enzyme (ACE) inhibitors are used widely in therapy for hypertension, congestive heart failure and myocardial infarction. However, coughing, one of their major adverse effects limits their use. It is documented that Asians are more liable to coughing than Europeans. The aim of this study was to investigate genetic polymorphism involved in ACE inhibitor-induced...
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