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Article

Mutation of tagO reveals an essential role for wall teichoic acids in Staphylococcus epidermidis biofilm development.

Microbiology (Reading, England) - 1 Feb 2011

Holland Linda M, Conlon Brian, O'Gara James P

Abstract excerpt

The icaADBC-encoded polysaccharide intercellular adhesin (PIA) and wall teichoic acids (WTA) are structural components of Staphylococcus epidermidis biofilms. Deletion of tagO, which encodes the first enzymic step in WTA biosynthesis, had pleiotropic effects, including enhanced intercellular aggregation and autolytic activity, and impaired biofilm production. The biofilm-negative phenotype of the tagO mutant,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21051486
DOI: 10.1099/mic.0.042234-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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