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Wall teichoic acid structure governs horizontal gene transfer between major bacterial pathogens

22 Aug 2013

Abstract excerpt

Mobile genetic elements (MGEs) encoding virulence and resistance genes are widespread in bacterial pathogens, but it has remained unclear how they occasionally jump to new host species. Staphylococcus aureus clones exchange MGEs such as S. aureus pathogenicity islands (SaPIs) with high frequency via helper phages. Here we report that the S. aureus ST395 lineage is refractory to horizontal gene transfer (HGT) with...

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PMID: 23965785
DOI: 10.1038/ncomms3345

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