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Article

A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity.

Molecular microbiology - 1 Aug 2007

Fedtke Iris, Mader Diana, Kohler Thomas, Moll Hermann, Nicholson Graeme, Biswas Raja, Henseler Katja, Götz Friedrich, Zähringer Ulrich, Peschel Andreas

Abstract excerpt

Many Gram-positive bacteria produce lipoteichoic acid (LTA) polymers whose physiological roles have remained a matter of debate because of the lack of LTA-deficient mutants. The ypfP gene responsible for biosynthesis of a glycolipid found in LTA was deleted in Staphylococcus aureus SA113, causing 87% reduction of the LTA content. Mass spectrometry and nuclear magnetic resonance spectroscopy revealed that the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17640274
DOI: 10.1111/j.1365-2958.2007.05854.x
PMCID: PMC2169524

Genes

LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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