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Genetic diversity of Staphylococcus aureus wall teichoic acid glycosyltransferases affects immune recognition

7 Dec 2022

Abstract excerpt

Staphylococcus aureus is a leading cause of skin and soft tissue infections and systemic infections. Wall teichoic acids (WTAs) are cell wall-anchored glycopolymers that are important for S. aureus nasal colonization, phage-mediated horizontal gene transfer, and antibiotic resistance. WTAs consist of a polymerized ribitol phosphate (RboP) chain that can be glycosylated with N -acetylglucosamine (GlcNAc) by three...

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PMID: 36748528
DOI: 10.1099/mgen.0.000902

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