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Isolation and Characterization of Biofilm Formation-Defective Mutants of <i>Staphylococcus aureus</i>

12 Dec 2006

Abstract excerpt

Staphylococcus aureus produces biofilm and this mode of colonization facilitates infections that are often difficult to treat and engender high morbidity and mortality. We have exploited bacteriophage Mu transposition methods to create an insertional mutant library in a highly biofilm-forming S. aureus clinical isolate. Our screen identified 38 insertions in 23 distinct genes together with one intergenic region...

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Share to Antimicrobial Resistance in Staphylococcus
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PMID: 17158901
DOI: 10.1128/iai.01143-06

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