Article
Does genetic regulation of IgE begin in utero? Evidence from T(H)1/T(H)2 gene polymorphisms and cord blood total IgE.
The Journal of allergy and clinical immunology - 1 Nov 2010
Hong Xiumei, Tsai Hui-Ju, Liu Xin, Arguelles Lester, Kumar Rajesh, Wang Guoying, Kuptsova-Clarkson Nataliya, Pearson Colleen, Ortiz Kathryn, Bonzagni Anthony, Apollon Stephanie, Fu Lingling, Pongracic Jacqueline A, Schleimer Robert, Holt Patrick G, Bauchner Howard, Wang Xiaobin
Abstract excerpt
BACKGROUND: Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allergies and atopic dermatitis. Cord blood IgE (CBIgE) is a recognized risk factor for the subsequent development of allergic diseases. In contrast with numerous genetic studies of total serum IgE in children and adults, limited genetic studies on...
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