Article
Gene-gene and gene-environment interactions on IgE production in prenatal stage.
Allergy - 1 Jun 2010
Yang K D, Chang J-C, Chuang H, Liang H-M, Kuo H-C, Lee Y-S, Hsu T-Y, Ou C-Y
Abstract excerpt
BACKGROUND: Prevalence of allergic diseases in children has increased worldwide over the past decades. Allergy sensitization may occur in fetal life. This study investigated whether gene-gene and gene-environment interactions affected cord blood IgE (CBIgE) levels. METHODS: A total of 575 cord blood DNA samples were subjected to a multiplex microarray for 384 single nucleotide polymorphisms (SNPs) in 159 allergy...
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