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Article

Maternal IgE Influence on Fetal and Infant Health

25 Apr 2025

Abstract excerpt

Immunoglobulin E (IgE) is the most recently discovered and evolved mammalian antibody type, best known for interacting with mast cells (MCs) as immune effectors. IgE-mediated antigen sensing by MC provides protection from parasites, venomous animals, bacteria, and other insults to barrier tissues exposed to the environment. IgE and MCs act as inflammation amplifiers and immune response adjuvants. Thus, IgE...

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PMID: 40281548
DOI: 10.1111/imr.70029

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