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Article

Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules

4 Nov 2010

Abstract excerpt

BACKGROUND: Elucidating the activation pattern of molecular pathways across a given tumour type is a key challenge necessary for understanding the heterogeneity in clinical response and for developing novel more effective therapies. Gene expression signatures of molecular pathway activation derived from perturbation experiments in model systems as well as structural models of molecular interactions ("model...

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PMID: 21050467
DOI: 10.1186/1471-2407-10-604

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