Article
Immunogenic Subtypes of Breast Cancer Delineated by Gene Classifiers of Immune Responsiveness.
Cancer immunology research - 1 Jul 2016
Miller Lance D, Chou Jeff A, Black Michael A, Print Cristin, Chifman Julia, Alistar Angela, Putti Thomas, Zhou Xiaobo, Bedognetti Davide, Hendrickx Wouter, Pullikuth Ashok, Rennhack Jonathan, Andrechek Eran R, Demaria Sandra, Wang Ena, Marincola Francesco M
Abstract excerpt
The abundance and functional orientation of tumor-infiltrating lymphocytes in breast cancer is associated with distant metastasis-free survival, yet how this association is influenced by tumor phenotypic heterogeneity is poorly understood. Here, a bioinformatics approach defined tumor biologic attributes that influence this association and delineated tumor subtypes that may differ in their ability to sustain...
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