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Article

Mutated Pathways as a Guide to Adjuvant Therapy Treatments for Breast Cancer.

Molecular cancer therapeutics - 1 Jan 2016

Liu Yang, Hu Zhenjun, DeLisi Charles

Abstract excerpt

Adjuvant therapy following breast cancer surgery generally consists of either a course of chemotherapy, if the cancer lacks hormone receptors, or a course of hormonal therapy, otherwise. Here, we report a correlation between adjuvant strategy and mutated pathway patterns. In particular, we find that for breast cancer patients, pathways enriched in nonsynonymous mutations in the chemotherapy group are distinct...

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Share to Antineoplastic Agents, Hormonal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26625895
DOI: 10.1158/1535-7163.MCT-15-0601
PMCID: PMC4707054

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