Article

Causal modeling dissects tumour-microenvironment interactions in breast cancer

2017-06-01

Abstract excerpt

Elucidating interactions between cancer cells and their microenvironment is a key goal of cancer research with implications for understanding cancer evolution and improving immunotherapy. Previous studies used association-based approaches to infer relationships in transcriptomic data, but could not infer the direction of interaction. Here we present a causal modeling approach that infers directed interactions betw...

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Literature Corpus work: 2e4ca22c-574b-5c06-83e2-3ad07c91738d
DOI: 10.1101/144832

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