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Article

Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles

4 Jan 2016

Abstract excerpt

Transcriptional programmes active in haematopoietic cells enable a variety of functions including dedifferentiation, innate immunity and adaptive immunity. Understanding how these programmes function in the context of cancer can provide valuable insights into host immune response, cancer severity and potential therapy response. Here we present a method that uses the transcriptomes of over 200 murine...

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PMID: 26725977
DOI: 10.1038/ncomms10248

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