Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of lymphocyte subsets in patients with common variable immunodeficiency reveals subsets of naive human B cells marked by CD24 expression.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2010

Vlková Marcela, Fronková Eva, Kanderová Veronika, Janda Ales, Ruzicková Sárka, Litzman Jirí, Sedivá Anna, Kalina Tomás

Abstract excerpt

Increased proportions of naive B cell subset and B cells defined as CD27(neg)CD21(neg)CD38(neg) are frequently found in patients with common variable immunodeficiency (CVID) syndrome. Current methods of polychromatic flow cytometry and PCR-based detection of κ deletion excision circles allow for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocyte Subsets
Share to CD24 Antigen
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Common Variable Immunodeficiency

Share to Gene Expression Regulation

Share to Lymphocyte Count

Share to Resting Phase, Cell Cycle

Source

Identifiers

PMID: 21041728
DOI: 10.4049/jimmunol.0903876

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21041728-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of lymphocyte subsets in patients with common variable immunodeficiency reveals subsets of naive human B cells marked by CD24 expression.PMID 21041728Read ↗

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells.Semantic proximity Read ↗

PID Comes Full Circle: Applications of V(D)J Recombination Excision Circles in Research, Diagnostics and Newborn Screening of Primary Immunodeficiency DisordersSemantic proximity Read ↗

B-cell replication history and somatic hypermutation status identify distinct pathophysiologic backgrounds in common variable immunodeficiencySemantic proximity Read ↗

B-cell maturation defects in common variable immunodeficiency and association with clinical features.Semantic proximity Read ↗

Decoupling activation and exhaustion of B cells in spontaneous controllers of HIV infectionSemantic proximity Read ↗

Use of V(D)J recombination excision circles to identify T- and B-cell defects and to monitor the treatment in primary and acquired immunodeficienciesSemantic proximity Read ↗

Dissection of the Pre-Germinal Center B-Cell Maturation Pathway in Common Variable Immunodeficiency Based on Standardized Flow Cytometric EuroFlow Tools.Semantic proximity Read ↗

Defective peripheral B cell selection in common variable immune deficiency patients with autoimmune manifestationsSemantic proximity Read ↗

Expansion of functionally anergic CD21-/low marginal zone-like B cell clones in hepatitis C virus infection-related autoimmunity.Semantic proximity Read ↗

Phenotypic and molecular characterization of human peripheral blood B-cell subsets with special reference to N-region addition and J kappa-usage in V kappa J kappa-joints and kappa/lambda-ratios in naive versus memory B-cell subsets to identify traces of receptor editing processes.Semantic proximity Read ↗

Intravenous immunoglobulin replacement therapy in common variable immunodeficiency induces B cell depletion through differentiation into apoptosis-prone CD21(low) B cells.Semantic proximity Read ↗

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.