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Article

B-cell maturation defects in common variable immunodeficiency and association with clinical features.

Pathology - 1 Apr 2008

Berglund Lucinda J, Wong Sue W J, Fulcher David A

Abstract excerpt

AIMS: Patients with common variable immunodeficiency (CVID) often have defects in post-antigenic B-cell differentiation with fewer memory B cells and impaired isotype switching. We aimed to classify CVID patients according to these defects and determine whether this predicted clinical manifestations. METHODS: We analysed the memory marker CD27, maturation marker CD21, and IgD on peripheral blood B cells from 31...

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Source

Identifiers

PMID: 18428049
DOI: 10.1080/00313020801911470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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