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Abcb1 Gene Polymorphisms Are Associated With Clinical Response to Nabiximols in Patients With Multiple Sclerosis-related Spasticity

2025-07-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system causing severe symptoms, including spasticity-related pain. Nabiximols (NBX), a drug combining Tetrahydrocannabinol and Cannabidiol, is approved for MS-associated spasticity. Despite NBX efficacy, only 60–70% of patients respond to treatment. This study explores whether genetic polymo...

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Literature Corpus work
5667995d-4487-582f-aa0f-89252f3e8c66
DOI
10.21203/rs.3.rs-7008522/v1
Open publication

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Abcb1 Gene Polymorphisms Are Associated With Clinical Response to Nabiximols in Patients With Multiple Sclerosis-related SpasticityDOI 10.21203/rs.3.rs-7008522/v1
<i>ABCB1</i>GENE POLYMORPHISMS ARE ASSOCIATED WITH CLINICAL RESPONSE TO NABIXIMOLS IN PATIENTS WITH MULTIPLE SCLEROSIS-RELATED SPASTICITYSemantic proximity
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