Article
Developmental dependence on NurRE and EboxNeuro for expression of pituitary proopiomelanocortin.
Molecular endocrinology (Baltimore, Md.) - 1 Jul 2008
Lavoie Pierre-Luc, Budry Lionel, Balsalobre Aurélio, Drouin Jacques
Abstract excerpt
Cell-specific expression of the pituitary proopiomelanocortin (POMC) gene depends on the combinatorial action of a large number of DNA-binding transcription factors (TFs). These include general and cell-restricted factors, as well as factors that act as effectors of signaling pathways. We have previously defined in the distal POMC promoter a composite regulatory element that contains targets for basic...
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