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Article

NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.

1 Nov 1994

Abstract excerpt

By analyzing the early genetic response of human T cells following mitogenic activation we have identified NOT, a member of the steroid/thyroid hormone family of receptors. NOT has all structural features of steroid/thyroid hormone receptors (C2C2 zinc-finger domain, ligand binding domain), but is rapidly and only very transiently expressed after cell activation, which is clearly at variance with classical...

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PMID: 7877627
DOI: 10.1210/mend.8.11.7877627

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