Mapping of HNF4α target genes in intestinal epithelial cells

doi:10.1186/1471-230x-9-68

Article

Mapping of HNF4α target genes in intestinal epithelial cells

17 Sept 2009

Abstract excerpt

BACKGROUND: The role of HNF4alpha has been extensively studied in hepatocytes and pancreatic beta-cells, and HNF4alpha is also regarded as a key regulator of intestinal epithelial cell differentiation. The aim of the present work is to identify novel HNF4alpha target genes in the human intestinal epithelial cells in order to elucidate the role of HNF4alpha in the intestinal differentiation progress. METHODS: We...

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