Article
Effects of chronic sleep restriction on the neuro-phenotypes of Ctnnd2 knockout mice.
Brain and behavior - 1 Jul 2023
Xu Man, Wang Xiaoya, Wang Luyi, Wang Shali, Deng Jing, Wang Yan, Li Yingbo, Pan Sen, Liao Ailing, Tao Yihao, Tan Shujiang
Abstract excerpt
INTRODUCTION: Sleep abnormalities are highly correlated with neurodevelopmental disorders, such as intellectual disability, attention deficit hyperactivity disorder, and autism spectrum disorders (ASD). The severity of behavioral abnormalities is correlated with the presence of sleep abnormalities. Based on previous research, we investigated that Ctnnd2 gene deletion in mice lead to ASD-like behaviors and...
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