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Article

Levetiracetam-mediated emotional behavior in heterozygous rolling Nagoya Ca(V)2.1 channel mutant mice.

Pharmacology, biochemistry, and behavior - 1 Sept 2010

Takahashi Eiki, Niimi Kimie, Itakura Chitoshi

Abstract excerpt

Ca(V)2.1, which is highly expressed in the nervous system, plays an essential role in presynaptic neurotransmitter release. Although recent data suggest that the antiepileptic drug levetiracetam (LEV) inhibits presynaptic Ca(V)2.1 activity, the precise physiological role of Ca(V)2.1/LEV-regulated emotional performance has not been elucidated. We examined whether Ca(V)2.1/LEV mediates emotional behavior using a...

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PMID: 20570694
DOI: 10.1016/j.pbb.2010.05.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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