Article
mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic β-cell.
Diabetes - 1 Jan 2011
Chen Jing, Gusdon Aaron M, Piganelli Jon, Leiter Edward H, Mathews Clayton E
Abstract excerpt
OBJECTIVE: To investigate whether a single nucleotide polymorphism (SNP) in the mitochondrial gene for NADH dehydrogenase 2 (mt-Nd2) can modulate susceptibility to type 1 diabetes in NOD mice. RESEARCH DESIGN AND METHODS: NOD/ShiLtJ mice conplastic for the alloxan resistant (ALR)/Lt-derived mt-Nd...
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