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Article

Role of genetics in resistance to type 1 diabetes.

Diabetes/metabolism research and reviews - 1 Nov 2011

Chen Jing, Gusdon Aaron M, Mathews Clayton E

Abstract excerpt

BACKGROUND: A single nucleotide polymorphism in the mitochondrial gene encoding NADH dehydrogenase subunit 2 (mt-ND2) has been associated with reduced incidence of human type 1 diabetes (T1D). We identified the orthologue of this mitochondrial single nucleotide polymorphism in mouse and using NOD mouse models linked this genetic polymorphism to T1D resistance. The mechanism how this single nucleotide polymorphism...

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Identifiers

PMID: 22069272
DOI: 10.1002/dmrr.1260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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