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Article

Psychophysical dissection of genotype effects on human bitter perception.

Chemical senses - 1 Jan 2011

Mennella Julie A, Pepino Marta Yanina, Duke Fujiko F, Reed Danielle R

Abstract excerpt

The purpose of this study was to define the effects of individual polymorphisms within the haplotypes of the TAS2R38 taste receptor gene on human bitter taste perception. A racially and ethnically diverse sample of children and adults (N = 980) was phenotyped for thresholds of 6-n-propylthiouracil (PROP) and genotyped for 3 polymorphisms of the TAS2R38 gene (A49P, V262A, I296V). Subjects were grouped according to...

Topics

Adolescent
Adult
Child
Child, Preschool
Choice Behavior
Female
Genotype
Humans
Male
Middle Aged
Polymorphism, Genetic
Psychophysiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, G-Protein-Coupled

Taste Threshold

Taste Receptors, Type 2

Source

Open in PubMed Open full text

Identifiers

PMID: 20980355
DOI: 10.1093/chemse/bjq106
PMCID: PMC3020389

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20980355-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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