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Article

Age modifies the genotype-phenotype relationship for the bitter receptor TAS2R38.

BMC genetics - 1 Jul 2010

Mennella Julie A, Pepino M Yanina, Duke Fujiko F, Reed Danielle R

Abstract excerpt

BACKGROUND: The purpose of this study was to investigate the effect of TAS2R38 haplotypes and age on human bitter taste perception. RESULTS: Children (3 to 10 yrs), adolescents (11 to 19 yrs) and adults (mostly mothers, 20 to 55 yrs (N = 980) were measured for bitter taste thresholds for 6-n-propylthiouracil (PROP) and genotyped for three polymorphisms of the AS2R38 gene (A49P, V262A, I296V). Subjects were...

Topics

Adolescent
Adult
Age Factors
Child
Child, Preschool
Ethnicity
Female
Genotype
Haplotypes
Humans
Male
Middle Aged
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, G-Protein-Coupled

Sex Factors

Taste Threshold

Taste Receptors, Type 2

Source

Open in PubMed Open full text

Identifiers

PMID: 20594349
DOI: 10.1186/1471-2156-11-60
PMCID: PMC3087510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20594349-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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