Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MDM2 and CDKN1A gene polymorphisms and risk of Kaposi's sarcoma in African and Caucasian patients.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Feb 2011

Tornesello Maria Lina, Buonaguro Luigi, Cristillo Medea, Biryahwaho Bennon, Downing Robert, Hatzakis Angelo, Alessi Elvio, Cusini Marco, Ruocco Vincenzo, Viviano Enza, Romano Nino, Katongole-Mbidde Edward, Buonaguro Franco M

Abstract excerpt

A single-nucleotide polymorphism in the MDM2 promoter (SNP309; rs2279744) causes elevated transcription of this major negative regulator of p53 in several cancer types. We investigated MDM2 SNP309 and CDKN1A (p21/Waf1/Cip1) codon 31 (rs1801270) polymorphisms in 86 cases of cutaneous Kaposi's sarc...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over
Share to Black People
Share to Cyclin-Dependent Kinase Inhibitor p21
Share to Proto-Oncogene Proteins c-mdm2
Share to Sarcoma, Kaposi
Share to Tumor Suppressor Protein p53
Share to White People
Share to Young Adult

Source

Identifiers

PMID: 20979563
DOI: 10.3109/1354750X.2010.525664

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20979563-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MDM2 and CDKN1A gene polymorphisms and risk of Kaposi's sarcoma in African and Caucasian patients.PMID 20979563Read ↗

MDM2 gene polymorphisms and risk of classic Kaposi's sarcoma among Iranian patients.Semantic proximity Read ↗

MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies.Semantic proximity Read ↗

MDM2 SNP309 polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.Semantic proximity Read ↗

Impact of MDM2 gene polymorphism on sarcoma risk.Semantic proximity Read ↗

The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis.Semantic proximity Read ↗

A functional SNP in the MDM2 promoter, pigmentary phenotypes, and risk of skin cancer.Semantic proximity Read ↗

Ewing Sarcoma: influence of TP53 Arg72Pro and MDM2 T309G SNPs.Semantic proximity Read ↗

MDM2 promoter SNP344T>A (rs1196333) status does not affect cancer risk.Semantic proximity Read ↗

MDM2 SNP309 contributes to tumor susceptibility: a meta-analysis.Semantic proximity Read ↗

Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers.Semantic proximity Read ↗

Investigation of the effect of MDM2 SNP309 and TP53 Arg72Pro polymorphisms on the age of onset of cutaneous melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.