MDM2 gene polymorphisms and risk of classic Kaposi's sarcoma among Iranian patients.

doi:10.1007/s00430-016-0491-9

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Article

MDM2 gene polymorphisms and risk of classic Kaposi's sarcoma among Iranian patients.

Medical microbiology and immunology - 1 Apr 2017

Varmazyar Sajad, Marashi Sayed Mahdi, Shoja Zabihollah, Tornesello Maria Lina, Buonaguro Franco M, Shahmahmoodi Shohreh, Safaie-Naraghi Zahra, Jalilvand Somayeh

Abstract excerpt

A single-nucleotide polymorphism (SNP) in the promoter region of MDM2 (SNP309T>G, rs2279744) has been shown to increase the expression of the MDM2 protein in various cancer types. However, only one study has analyzed the role of the MDM2 polymorphism in the development of Kaposi's sarcoma (KS). The association of MDM2 SNP309 with classic KS risk was evaluated in 79 Iranian patients with classic KS and 123 healthy...

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PMID: 28083704
DOI: 10.1007/s00430-016-0491-9

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MDM2

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