Article
MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma.
Cancer research - 1 Nov 2010
Voortman Johannes, Goto Akiteru, Mendiboure Jean, Sohn Jane J, Schetter Aaron J, Saito Motonobu, Dunant Ariane, Pham Trung C, Petrini Iacopo, Lee Alan, Khan Mohammed A, Hainaut Pierre, Pignon Jean-Pierre, Brambilla Elisabeth, Popper Helmut H, Filipits Martin, Harris Curtis C, Giaccone Giuseppe
Abstract excerpt
This study determined whether expression levels of a panel of biologically relevant microRNAs can be used as prognostic or predictive biomarkers in patients who participated in the International Adjuvant Lung Cancer Trial (IALT), the largest randomized study conducted to date of adjuvant chemotherapy in patients with radically resected non-small cell lung carcinoma (NSCLC). Expression of miR-21, miR-29b,...
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