Article
Prognostic significance of microRNA expression in completely resected lung adenocarcinoma and the associated response to erlotinib.
Medical oncology (Northwood, London, England) - 1 Oct 2014
Yan Guanzhong, Yao Ruyong, Tang Dongfang, Qiu Tong, Shen Yi, Jiao Wenjie, Ge Nan, Xuan Yunpeng, Wang Yongjie
Abstract excerpt
The mechanism of action of oncogenic or tumor suppressor microRNAs is not well understood. We examined the microRNA expression profile in completely resected lung adenocarcinoma and examined the associated response to erlotinib. The lung adenocarcinoma tissue and adjacent normal lung parenchyma of 226 stage IIB and IIIA patients who underwent complete resection were obtained for two separate retrospective...
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