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Article

Let-7g and miR-21 expression in non-small cell lung cancer: correlation with clinicopathological and molecular features.

International journal of oncology - 1 Sept 2013

Capodanno Alessandra, Boldrini Laura, Proietti Agnese, Alì Greta, Pelliccioni Serena, Niccoli Cristina, D'Incecco Armida, Cappuzzo Federico, Chella Antonio, Lucchi Marco, Mussi Alfredo, Fontanini Gabriella

Abstract excerpt

MicroRNAs (miRNAs) play a key role in cancer pathogenesis and are involved in several human cancers, including non-small cell lung cancer (NSCLC). This study evaluated Let-7g and miR-21 expression by quantitative real-time PCR in 80 NSCLC patients and correlated the results with their main clinicopathological and molecular features. MiR-21 expression was significantly higher in NSCLC tissues compared to...

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Share to Aged, 80 and over
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23820752
DOI: 10.3892/ijo.2013.2003

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