Article
Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication.
Journal of virology - 1 May 2006
Bouchard Michael J, Wang Lihua, Schneider Robert J
Abstract excerpt
The hepatitis B virus (HBV) X protein (HBx) is a multifunctional regulator of cellular signal transduction and transcription pathways and has a critical role in HBV replication. Much of the cytoplasmic signal transduction activity associated with HBx expression and its stimulation of viral replication is attributable to HBx-induced activation of calcium signaling pathways involving Pyk2 and Src tyrosine kinases....
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