Article
Genotypic profiling of 452 choroidal melanomas with multiplex ligation-dependent probe amplification.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2010
Damato Bertil, Dopierala Justyna A, Coupland Sarah E
Abstract excerpt
PURPOSE: Metastasis from uveal melanoma occurs almost exclusively with tumors showing chromosome 3 loss. We used multiplex ligation-dependent probe amplification (MLPA) to detect chromosome 1p, 3, 6p, 6q, 8p, and 8q abnormalities in uveal melanomas. The purpose of this study was to correlate our...
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