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Article

Genomic profile of 320 uveal melanoma cases: chromosome 8p-loss and metastatic outcome.

Investigative ophthalmology & visual science - 23 Aug 2013

Ewens Kathryn G, Kanetsky Peter A, Richards-Yutz Jennifer, Al-Dahmash Saad, De Luca Maria Carla, Bianciotto Carlos G, Shields Carol L, Ganguly Arupa

Abstract excerpt

PURPOSE: Uveal melanoma (UM) was a fatal malignancy in 40% to 50% of cases. The aim of this study is to evaluate the independent contributions of chromosome 1, 3, 6, and 8 abnormalities for prognostication of metastasis, and to define multichromosome copy number aberration (CNA) signatures that can be used to evaluate risk. METHODS: A series of 320 UM were analyzed for chromosome 1, 3, 6, and 8 abnormalities...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23821189
DOI: 10.1167/iovs.13-12195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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