Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Determinants of RasC specificity during Dictyostelium aggregation.

The Journal of biological chemistry - 31 Dec 2010

Bolourani Parvin, Spiegelman George, Weeks Gerald

Abstract excerpt

RasC is required for optimum activation of adenylyl cyclase A and for aggregate stream formation during the early differentiation of Dictyostelium discoideum. RasG is unable to substitute for this requirement despite its sequence similarity to RasC. A critical question is which amino acids in RasC are required for its specific function. Each of the amino acids within the switch 1 and 2 domains in the N-terminal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Blotting, Western
Share to Cyclic AMP

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Densitometry

Share to Dictyostelium

Share to Protozoan Proteins

Share to ras Proteins

Share to Transgenes

Source

Open in PubMed Open full text

Identifiers

PMID: 20971846
DOI: 10.1074/jbc.M110.181115
PMCID: PMC3009863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Determinants of RasC specificity during Dictyostelium aggregation.PMID 20971846Read ↗

RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation.Semantic proximity Read ↗

Chemoattractant-induced Ras activation during Dictyostelium aggregation.Semantic proximity Read ↗

A temperature-sensitive adenylyl cyclase mutant of Dictyostelium.Semantic proximity Read ↗

amiB, a novel gene required for the growth/differentiation transition in Dictyostelium.Semantic proximity Read ↗

A secondary disruption of the dmpA gene encoding a large membrane protein allows aggregation defective Dictyostelium rasC- cells to form multicellular structures.Semantic proximity Read ↗

Insights Into Aggregation-Delayed Phenotype of Dictyostelium discoideum.Semantic proximity Read ↗

Phenotypic changes induced by a mutated ras gene during the development of Dictyostelium transformants.Semantic proximity Read ↗

A novel Dictyostelium RasGEF required for chemotaxis and development.Semantic proximity Read ↗

The Dictyostelium homologue of mammalian soluble adenylyl cyclase encodes a guanylyl cyclase.Semantic proximity Read ↗

An adenylyl cyclase that functions during late development of Dictyostelium.Semantic proximity Read ↗

Molecular genetics of signal transduction in Dictyostelium.Semantic proximity Read ↗

Dictyostelium RasG is required for normal motility and cytokinesis, but not growth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.