CLU rs2279590 polymorphism contributes to Alzheimer's disease susceptibility in Caucasian and Asian populations.

doi:10.1007/s00702-014-1260-9

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CLU rs2279590 polymorphism contributes to Alzheimer's disease susceptibility in Caucasian and Asian populations.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2015

Zhang Shuyan, Zhang Donghui, Jiang Yongshuai, Wu Lina, Shang Hong, Liu Jiafeng, Feng Rennan, Liao Mingzhi, Zhang Liangcai, Liu Yong, Liu Guiyou, Li Keshen

Abstract excerpt

It is reported that CLU rs2279590 polymorphism is significantly associated with Alzheimer's disease (AD) in European ancestry. Recent studies investigated rs2279590 polymorphism in Asian population (Chinese, Japanese and Korean). Four studies showed negative association and two studies showed weak association between rs2279590 and AD. We believe that the weak association or no association may be caused by the...

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PMID: 24947876
DOI: 10.1007/s00702-014-1260-9

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