Article
Association of angiotensin II type 1 receptor (A1166C) gene polymorphism and its increased expression in essential hypertension: a case-control study.
PloS one - 1 Jan 2014
Chandra Sudhir, Narang Rajiv, Sreenivas Vishnubhatla, Bhatia Jagriti, Saluja Daman, Srivastava Kamna
Abstract excerpt
OBJECTIVES: Hypertension is one of the major cardiovascular diseases. It affects nearly 1.56 billion people worldwide. The present study is about a particular genetic polymorphism (A1166C), gene expression and protein expression of the angiotensin II type I receptor (AT1R) (SNP ID: rs5186) and its association with essential hypertension in a Northern Indian population. METHODS: We analyzed the A1166C polymorphism...
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